THE EFFECT OF HIGH DOSES OF VITAMIN D3 IN PRESENCE OF VITAMIN C ON THE KIDNEY OF DOMESTIC MALE RABBITS

Abstract

Since the corona virus is spreading, many doctors advise taking vitamin D to avoid contracting it. However, some people misused it without considering the potential toxicity. Because of this reason, in this study, male rabbits were used to examine the effects of varying vitamin D3 dosages on the kidney's physiology and histology. For three months, male rabbits were injected with vitamin D3 at doses of 200,000, 400,000, 600,000 and 800,000IU per month. Numerous physiological signs in the kidney of the rabbit after treatment, such as, elevated of urea concentrations as well as creatinine in the blood serum. Also, there were some histological signs included hyaline, atrophy and focal calcifications.